Friday, November 30, 2012

Proteins that work at the ends of DNA could provide cancer insight

ScienceDaily (Nov. 29, 2012) ? New insights into a protein complex that regulates the very tips of chromosomes could improve methods of screening anti-cancer drugs.

Led by bioengineering professor Sua Myong, the research group's findings are published in the journal Structure.

Myong's group focused on understanding the proteins that protect and regulate telomeres, segments of repeating DNA units that cap the ends of chromosomes. Telomeres protect the important gene-coding sections of DNA from loss or damage, the genetic equivalent of aglets -- the covering at the tips of shoelaces that keep the ends of the laces from unraveling or fraying.

Telomeres play an important role in cell aging and death, since each time a cell divides, a little bit is lost from the end of the telomere. Thus, cell biologists postulate that telomere length can determine the lifespan of a cell. Cancer cells, however, have a way to get around this limitation: An enzyme called telomerase that adds length to telomeres is highly active in cancer cells. This allows cancer cells to divide in perpetuity, running amok through tissues and systems.

"Cancer researchers want to get a hold of this problem, control this indefinite lengthening of the telomeres," said Myong, who also is affiliated with the Institute for Genomic Biology at the U. of I. "A lot of the anti-cancer drugs are targeted directly to these telomeres so that they can inhibit telomerase activity. The proteins we study regulate the activity of telomerase."

Using a technique developed at Illinois that allows researchers to watch single molecules interact in real time, Myong's group determined how two proteins called POT-1 and TTP-1 bind to the telomere. POT-1 protects the fragile telomere ends from being attacked by other regulatory proteins that might mistake the end for a broken or damaged area of DNA. When POT-1 and TTP-1 work together in a complex, they promote telomerase activity, an interesting target for cancer researchers.

The group found that on its own, POT-1 binds to the folded-up telomere in distinct steps at particular points in the telomere's DNA sequence, unfolding the telomere in a stepwise manner. However, the POT-1/TTP-1 complex surprised the researchers by binding, then freely sliding back and forth along the telomere end.

"Instead of stepwise binding, what we saw was a mobile protein complex, a dynamic sliding motion," Myong said. "Somehow it was as if the static binding activity of POT-1 is completely lost -- the protein complex just slid back and forth. We were able to reproduce the data and confirm it with many different tail lengths of the telomeric DNA and we know now that the contact between POT-1 and the telomere is somehow altered when the partner protein comes and binds."

Next, the researchers will add telomerase and see how the sliding activity of the POT-1/TTP-1 complex affects telomerase activity. Myong postulates that the sliding may promote telomerase activity -- and thus telomere lengthening -- by making the end of the telomere accessible for the telomerase enzyme to bind.

"We are excited about the possibility that this kind of mobility can increase the telomerase extension activity," Myong said. "It's somehow engaging the enzyme so that it can stay bound to the DNA longer. So it must involve a direct interaction."

Ultimately, understanding the POT-1/TTP-1 complex gives drug developers a new target for anti-cancer drugs, and the assay Myong's group used to monitor the complex could offer a venue for evaluating telomere-targeting drugs.

"We want to extend our a basic science knowledge in telomere biology into causes of cancer and we hope that our assay can be useful for telomere-targeted drug screening," Myong said.

The American Cancer Society and the Human Frontier Science Research Program supported this work.

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Story Source:

The above story is reprinted from materials provided by University of Illinois at Urbana-Champaign.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Helen Hwang, Noah Buncher, Patricia?L. Opresko, Sua Myong. POT1-TPP1 Regulates Telomeric Overhang Structural Dynamics. Structure, 2012; 20 (11): 1872 DOI: 10.1016/j.str.2012.08.018

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/H7VyF-YvzO4/121129152029.htm

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Interview: C.C. Chapman on Amazing Things Will Happen ...

Amazing Things Will HappenAs children we dream.

We manufacture these massively multicolored stories which are acted-out. And devoid of any reservations. But as adults we suppress our dreams for a more practical way of living. In many cases a safer ? predictable life. And while there is nothing wrong with traveling the road most traveled. Often times, our compromises lead us to an unfulfilled life.

I have traveled the road most traveled. Because it was expected of me. But over the past year, mentors such as Michael Hyatt gave me the tools to start dreaming again. But C.C. Chapman ?told? me that there is nothing shameful in actually pursuing my dreams.

So here I am with my personal photography blog. Where I also pursue my dreams of being a writer. And because Chapman as been such a positive influence in my life, I asked if I could interview him. And he said ?yes!? :-)

Why did you decide to write ?Amazing Things Will Happen?? And how did ?Managing the Gray? influence that choice?

I didn?t have a choice about writing this book. It has been nagging to get out of my head for years and the time was finally right.

I had already written out the outline before starting Content Rules and when Ann asked me to write that with her I put this book on the back burner. It was never a question of not writing it, just a question of when.

Managing the Gray did influence the book because I heard back from listeners more than once, ?why don?t you write a book about this?? so I knew that there was already an audience for it when I found the time.

The biggest motivator for writing the book is that my kids are becoming teenagers and I wanted them to have a handy guide for living a great life. Sure, I talk to them all the time about what they want to be when they grow up and their different options but I thought it would be helpful to have an actual guide they could go to. I?m eager to see what they think about it after reading it. (they both currently are)

You mention the importance of always having a notebook. Why is having a notebook so important?

Because you never know when an idea is going to strike you and having a notebook that you can jot it down in makes sure you don?t lose any. Plus, while technology is great and I use Evernote as my virtual brain, being able to write and sketch on paper still hasn?t been replaced by any technology as far as I?m concerned.

In addition it is great to spend quiet time with a notebook. Sitting in a coffee shop or a park bench with simply a notebook and a pen is a great way to let the ideas flow. I talk about the importance of getting away from technology sometimes and a notebook is a great travel companion.

I see that creating lists is an important tool for you. But what do you tell people who make ?To Do Lists? and never check off a single task?

Stop making lists!! A list is only a valid tool if you actually cross items off it.

I am a big list maker because it forces me to focus on the most important tasks that need to get done. I quite often will grab a post it and write out the 3-5 things that I want to get done on any given day so that I can focus on those. If you make the list too long then you?ll never get it done and that isn?t good either.

Walking the road less traveled is terrifying for many. What is your advice, to those people, on how to start the journey?

Take the first step and then keep on walking.

It really is that simple and I talk about it in much more depth in the book, but once you choose the path that you want to take you are the only person who can actually start walking down it. Yes, there will always be risks, turns and rough patches because that is how life is.

Call To Action

Pursue your dreams. Allow yourself to be a child whose imagination runs uninhibited. Permit yourself to chase the dream of being a photographer or a writer or a world traveler or where ever your dreams take you.

Source: http://www.business2community.com/expert-interviews/interview-c-c-chapman-on-amazing-things-will-happen-0344521

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Testicular cancer risk tripled in boys whose testes fail to descend

ScienceDaily (Nov. 28, 2012) ? Boys whose testes have not descended at birth -- a condition known as cryptorchidism -- are almost three times as likely to develop testicular cancer in later life, finds an analysis of the available evidence published online in Archives of Disease in Childhood.

The findings prompt the authors to ask whether boys with the condition should be regularly monitored to lessen the potential risk

Cryptorchidsim, where testes fail to descend into the scrotum and are retained within the abdomen, is the most common birth defect in boys, affecting around 6% of newborns.

The authors trawled the Embase and Medline databases for studies, which looked at the potential link between cryptorchidism as an isolated abnormality and testicular cancer risk, and which had been published between January 1980 and December 2010.

They found 735 relevant papers, published in English, among which 12 studies matched the inclusion criteria and covered corrective surgery (orchidopexy).

The haul included 9 case-control studies, involving 2281 cases of testicular cancer, which had been diagnosed between the ages of 15 and 75 between 1965 and 2006, and 4811 controls.

And it included 3 cohort studies, which regularly monitor similar groups of people over the long term to see what happens to them.

These studies involved more than 2 million boys whose health was tracked for a cumulative period of 58 million person years. Boys with cryptorchidism who developed testicular cancer totalled 345.

Boys with cryptorchidism in the case-control group were almost 2.5 times as likely to develop testicular cancer as those without the condition.

And those in the cohort studies were almost 4 times as likely to develop the disease if their testes had not descended at birth.

The authors calculated that, on the basis of the two sets of figures, boys with isolated cryptorchidism are almost three times as likely to develop testicular cancer in later life.

Testicular cancer is the most common cancer in men aged between 20 and 45, and rates have increased substantially worldwide over the past few decades, the authors point out.

In the UK, the number of new cases almost doubled between 1975-7 and 2006-8, rising from 3.4/100 000 men to 6.9/100 000.

"Many important unanswered questions remain, such as how laterality, degree of descent, and surgical correction affect the malignant potential of the [undescended] testis," write the authors.

And they add: "The most poignant question this study raises, however, is whether the risk of malignant transformation is sufficiently significant to warrant regular follow-up, as is the case with other premalignant states."

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Story Source:

The above story is reprinted from materials provided by BMJ-British Medical Journal.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. S. Z. L. Lip, L. E. D. Murchison, P. S. Cullis, L. Govan, R. Carachi. A meta-analysis of the risk of boys with isolated cryptorchidism developing testicular cancer in later life. Archives of Disease in Childhood, 2012; DOI: 10.1136/archdischild-2012-302051

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/4fvfzpkF5dE/121129093947.htm

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Is $100 per month enough to invest in the stock market? ? Roth IRA ...

I?m just starting out my career. And I would like to know is the stock market the wise choice to invest the $100 per month? Or maybe Roth IRA?s? Thanks!!!!!!!!!

Question 2: Should I start investing into my employer?s 401 k plan? The deal is, I am planning to move to another state within 2 years from now. Should I still contribute to the 401k or not?

Source: http://rothira.solve-up.com/roth-ira/is-100-per-month-enough-to-invest-in-the-stock-market/

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Branden R. Williams, Business Security Specialist ? The Biggest ...

The PCI Council has been pretty influential in our lives since its inception on September 7, 2006. They were handed control of the PCI Data Security Standard and have turned it into a cascading group of standards that govern (or recommend controls) for nearly every aspect of payment acceptance and processing. So it almost seems like this PCI problem is sort of solved, doesn?t it?

Encrypted stories, by FeatheredTar

When you look at the PCI DSS ecosystem, many of the big rocks have already been addressed. This has some interesting side effects, one of which is a camp of merchants that have been hounded to get compliant (Levels 1-3) and a mass of merchants that have no clue about PCI DSS until they are breached (Level 4). Keep in mind, the number of merchants that make up the latter group is much larger than the former. For every one of those larger merchants, there are around 1,800 of the smaller ones in the US alone. That large group of merchants which collectively does process the majority of transactions (around 65-70%) only represents ~.05% of the total merchant population in the US.

A breach at one of those larger merchants is more significant than one at a smaller merchant due to the numbers of transactions they process. But what often happens is that smaller merchants don?t know they need to comply, have never heard of PCI DSS, and end up going out of business. Sure, a breach of 5,000 cards is significant in fines to a small merchant, but to the overall ecosystem it is a blip considering that there are more than 600 million cards issued in the US alone.

The PCI Council has recently accelerated compliance among certain groups of merchants through their Point-to-Point Encryption (P2PE) guidance, whereby some merchants have been able to remove significant portions of their infrastructure from scope. We saw at the North American Community Meeting that the Hardware Encrypt/Hardware Decrypt (HW/HW) standard is approved and manufacturers are invited to submit their terminals for testing and approval. This is great for merchants who use HW/HW terminals, but there are few Level 4 merchants who are willing to swap out terminals to be able to say they comply with this standard.

Chatuchak Market, by Martin Fischer

Some of my most enlightening consulting work in the PCI DSS space is with large franchisors?those common brands you see in small shops on every street corner that are really owned by Joe Main Street, not a giant corporation. If Joe Main Street had a windfall of $10,000 to invest in his business, he is definitely not buying new P2PE complaint hardware terminals (or compliant card readers for integrated POS, another huge problem for this community).? My experience with these merchants is that this type of equipment gets replaced when it is beyond repair. Yet, in reality, an investment like that could protect his business from closure due to a payment card breach.

So if we know that a small merchant needs assistance but is unwilling to pay thousands of dollars to get that assistance, what can we do? One thing we learned at the community meeting is that the Software Encrypt/Hardware Decrypt (SW/HW) standard has been given some ambiguous release date in 2013-2014, behind a Hardware Encrypt/Software Decrypt (HW/SW) standard that doesn?t stand to help anyone in the merchant community. The biggest thing the PCI Council can do is to prioritize the SW/HW P2PE requirements such that the 99.95% merchant community could have access to cheap, but effective, encryption routines to take huge portions of their networks out of scope.

I can hear you say, ?But Branden, software encryption isn?t better than hardware encryption!? I?m not suggesting that it is. Equating hardware encryption to software encryption is an apples to oranges comparison. What I would suggest is that software encryption (easy and quick to adopt) is preferable to no encryption?essentially an apples to no apples comparison?and giving merchants an approved vehicle by which they can accomplish this can make a big difference in reducing risk. Using public-key cryptography systems, these merchants could improve their security posture by an order of magnitude using the same proven (and approved by PCI DSS) technology that protects online transactions in the browser today.

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If you're new here, you may want to subscribe to my RSS feed. For information on my book and other publications, click here.

Source: https://www.brandenwilliams.com/blog/2012/11/29/the-biggest-thing-the-pci-council-can-do/

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Ronda Rousey: ?I try to have as much sex as possible before I fight?

UFC/Strikeforce women's bantamweight champion Ronda Rousey appeared on Jim Rome's show on Wednesday. What does the champion use as her training secret? Does she have high-level training methods not available to amateur athletes and workout warriors?

Nope. She likes to have as much sex as possible before fights. Though Mick advised Rocky that women weaken the legs, Rousey believes it has the opposite effect on women.

"For girls it raises your testosterone, so I try to have as much sex as possible before I fight actually. Not with like everybody, I don't put out like a Craigslist ads or anything, but if I got a steady I'm going to be like, 'Yo, fight time's coming up,'" Rousey said.

It clearly works for her. Rousey has steamrolled every opponent she has faced on her way to the championship and a 6-0 record. She's won every fight with a first-round submission, and she recently was named the first woman in the UFC. Though her opponent and the date for her first UFC fight are currently unknown, UFC president Dana White said her bout will be a main event on a pay-per-view.

Rousey is also a two-time Olympian, and she won a bronze medal for judo in 2008. It was a fight before the Beijing Olympics that made her think she could be successful in the cage.

"Yes. I got in a fight with a couple of guys at the end of 2007 in a movie theater. It was four couples so four guys and one girl tried to get into it. And I had two friends with me. But I was only really handling two guys by myself. They sued me for assault because it didn't really go too well for them. I guess if you lose a fight in Santa Monica the next option is to sue. Everyone in the theater was cheering for me. I was thinking I might have a future in this. It was before the whole MMA thing."

Source: http://sports.yahoo.com/blogs/mma-cagewriter/ronda-rousey-try-much-sex-possible-fight-171940850--mma.html

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Disruption of water delivery could devastate L.A. County economy

An earthquake that shuts down water deliveries from Northern California for a year could devastate the Los Angeles County economy, costing $55 billion and wiping out a half-million jobs, according to a new study.

The research by a team of economists attempts to gauge the effects of a major earthquake disrupting water deliveries from the Sacramento-San Joaquin delta, which provides roughly a quarter of Southern California's water supply.

The report concludes that L.A. County could fairly easily weather a six-month stop in deliveries from the north by ramping up conservation efforts and using reserves stored in Southland reservoirs. But if the California Aqueduct that carries water south from the delta is dry for a year or more, the county economy would suffer severely, the researchers found.

"There are a couple of different ways to deal with this," said Adam Rose, the study's lead author and a research professor at USC's Price School of Public Policy. "Protect the California Aqueduct at its source" and "make us more resilient" by investing in additional regional storage, desalination and other alternative water supply sources, he said.

The study was commissioned by the Los Angeles County Economic Development Corp. and partly funded by several water agencies, including the Metropolitan Water District of Southern California and the Los Angeles Department of Water and Power.

It was released as the state is considering a major redesign of the way it gets water from the delta, which supplies part of the Bay Area as well as the San Joaquin Valley and Southern California. Under the proposal, water would be diverted from the Sacramento River into twin water tunnels running under the delta to pumps that fill southbound aqueducts.

The tunnel project is intended in part to make deliveries less vulnerable to disruption by an earthquake, which could damage delta levees, allowing saltwater to rush in from San Francisco Bay and contaminate water exports.

The researchers used modeling to estimate the economic effect of a loss of Northern California imports for up to three years, assuming the shortages would drive up water rates and restrict local deliveries. They concluded that halting deliveries for a year during a drought could cost the county as much as $55.6 billion in gross domestic product and as many as 550,000 jobs. In times of normal rainfall, a two-year shutdown would cut the county's gross domestic product by $75 billion and about a half-million jobs.

Those losses could be reduced substantially, Rose said, if the residential sector absorbed most of the water shortages, leaving the commercial and industrial sectors relatively unaffected. The economic effect would also be less if water rates did not rise.

The study results differ significantly from a cost-benefit analysis of the tunnel proposal conducted by David Sunding, a UC Berkeley professor of natural resource economics. Estimating the statewide effect of earthquake-related disruptions to delta deliveries, Sunding concluded the economic hit to urban ratepayers would range from $684 million for a six-month outage to $9 billion for a three-year halt.

Sunding "clearly did find significant economic impact as well," said Roger Patterson, assistant general manager of the Metropolitan Water District. "His numbers are much less. This is probably a case of economists needing to compare notes and understand what methods were used."

bettina.boxall@latimes.com

Source: http://feeds.latimes.com/~r/latimes/news/science/~3/Kd0ub8KhA4w/la-me-water-economy-20121130,0,2693930.story

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Marginal Income Tax Rates and Small Business: The Economics of ...

November 28th, 2012

John Boehner today?again argued against returning to the top marginal income tax rates of the prosperous Clinton era (themselves relatively low by historical standards) by referring to their supposed negative effects on ?job creation? by small businessmen. ? Though the real-world economic effect is likely to minimal, there are sound arguments from economic theory that the increase might actually create jobs.

Labor costs are subtracted from business income before arriving at the profit that might then be taxed, whether at corporate or individual rates. ? Workers are not hired out of a business?s profits, they are hired using before-tax cash. ? If the small business is not making a profit, ?a (unitary) small business owner is not paying the top tax rate, and this is all irrelevant. ? ?So hiring a worker is something a profitable small business owner can do to reduce its exposure to tax. ? It will create more firm value for the future, so if the small business owner later sells (and realizes value that is taxable at lower capital gains rates), the effect will be to have avoided the income tax now to pay lower capital gains tax later. ? Even if they pay income tax on increased profit later, the tax will have been deferred. ?So economic theory says that a higher marginal tax rate will be an extra incentive to avoid realizing profits now, especially if it can be turned into a capital gain rather than ordinary income later.

If the small business person has an after-tax income target that they are trying to meet, then a higher average tax rate will require more profits to reach this target, so in fact increasing both marginal and average rates may be better (so eliminating deductions might actually be worse than increasing marginal rates ? and not just because of the fairness issue that cutting deductions favors the super-rich compared to the merely rich, or because many mechanisms for recapturing deductions create a ?bubble? of higher marginal rates for a certain income segment).

In the real world all of these marginal incentive effects are small, certainly in regards to the difference between 36 and 39.6%? so the talk of incentives is ?really an academic discussion? the major point is that Boehner and others who talk about higher individual income tax rates as a disincentive to hire workers are flat wrong just because labor costs come from pre-tax firm funds, not after-tax funds.

Source: http://www.samefacts.com/2012/11/uncategorized/marginal-income-tax-rates-and-small-business-the-economics-of-the-stupid-party/

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Book Review: "Tap Dancing to Work" -- The Latest Buffett Bio : The D ...

In her authorized 2009 biography of American business icon Warren Buffett, The Snowball, ?Alice Schroeder admirably captured how Buffett?s long and successful business career resulted in the?accumulation of not only vast wealth, but also of an impressively?large and loyal network of close friends. Among Buffett?s buddies is Fortune Magazine?s editor-at- large, Carol Loomis. Loomis not only befriended Buffett and his wife, along the way becoming a Berkshire shareholder and an occasional Buffett bridge partner, but also for the last 35 years she has served as the pro bono editor of Buffett?s widely-read and admired annual letter to Berkshire shareholders.

?

Owing to her unique access to Buffett, Loomis has written a number of perceptive and even revelatory Fortune articles about Buffett. She also provided editorial direction to Fortune colleagues on numerous other articles about Buffett that appeared in the magazine. Many of these articles from the Fortune archives have been collected in a new book, entitled Tap Dancing to Work: Warren Buffett on Practically Everything, 1966-2012. The title is a reference to Buffett?s frequent statement that he enjoys his work so much that he ?tap dances to work ? As befits a book with such an upbeat title, the book is a rousing celebration of Buffett?s?life and business success . (A disclosure statement seems appropriate at this point: I own BRK.B shares, although not merely as many as I wish I did.)

?

If Schroeder?s book represented a personal biography of Buffett, Loomis?s book is more of a business biography. The Fortune articles about Buffett are arranged essentially in chronological order, as a result of which the book charts the long arc of Buffett?s business life. Buffett himself recently said that ?when you look at Berkshire, you are looking across corporate America.? Reading this book is in many ways a guided tour not only through Buffett?s career and business success, but also through the ebbs and flows of the American business scene over the last four decades.

?

There is much to commend and admire about this book. Among other things, the book includes several excellent examples of masterful magazine writing. Loomis?s own April 1988 article entitled ?The Inside Story of Warren Buffett? (a version of which can be found here) may be the single best short description available of Buffett and his business philosophy. (Indeed, if you read Loomis?s article, you arguably could dispense with the need the now growing collection of book-length Buffett biographies.)

?

Loomis?s October 1997 article entitled ?The Wisdom of Salomon?? (a version of which can be found here,), about Buffett?s fraught 1991 involvement in the near-collapse of the Salomon Brothers investment banking firm, is a gripping account of perhaps the greatest crisis in Buffett?s long career.

?

There are also a number of?minor?gems in this book, including a charming 1978 article about how?a still?relatively unknown Buffett helped produce an enormous investment profit for the?endowment?of tiny Grinnell College (on whose Board?of Trustees Buffett served at the time) through a clever and well-timed acquisition of a Dayton, Ohio television station. (The book also reveals that the Grinnell trustees included, during the time that Buffett served on the board, one of the founders of Intel and some guy named Steve Jobs. I have no idea how Grinnell managed to recruit so many corporate titans to its board. I do know that the current value of the college?s endowment is approximately $1.5 billion -- or more than $800,000 for each of the school?s 1,700 students.)

?

The book also reprints a 1995 book review written by Bill Gates about yet another Buffett biography. Gates?s book review contains an amusing retelling of the occasion in 1991 when Gates and Buffett first met, as well as a touching account of the friendship of the two men. (In an introduction to the Gates piece, Loomis reports that Gates had not wanted to come to the event at which he met Buffett, but was only persuaded to attend after he learned that Washington Post CEO Katherine Graham was going to be there as well. Loomis also reports that while Buffett arrived at the event in the back seat of Post Managing Editor Meg Greenfield?s ?ancient and cramped? Subaru,??Bill and his girlfriend (soon to be wife) Melinda French, arrived more grandly, in a helicopter.?)

?

Another very interesting feature of this book is how its chronological structure?highlights ?the way earlier events can foreshadow later developments (even though not apparent at the time). For example, Loomis?s riveting account of the Salomon fiasco provides an almost painful premonition of the Lehman collapse 17 years later. And you can?t read the excerpt in the book of Buffett?s 2002 letter to Berkshire shareholders characterizing derivatives as ?weapons of financial mass destruction? without thinking about what happened at AIG just six years later. Indeed, if one were to write a work of fiction with so much heavy-handed foreshadowing, most readers would immediately reject it as hopelessly contrived.

?

While this book is both enlightening and enjoyable to read, it has its shortcomings. Among other things, even though there were slight mentions of Buffett in the magazine at earlier times (including one April 1966 item that managed to misspell Buffett?s last name), Fortune didn?t write about Buffett as Buffett until the late 70s, and didn?t get around to writing a feature article about him until the early 80s. By that time, Buffett was already in his 50s and by any measure already a phenomenally successful investor and businessman. Simply put, ?other than Loomis?s one article mentioned above, this book lacks a detailed examination of how Buffett got started and how he developed the iron-clad business principles that have guided him ever since.

?

There is another shortcoming with this book?s approach, one that is perhaps an inevitable result of the fact that the book is an anthology of magazine articles written over many decades. Its coverage of Buffett, as thorough as it was, has been episodic and intermittent. Loomis makes up for this somewhat with a running commentary interspersed throughout the book, but inevitably there are gaps. Some of the gaps are huge.

?

For example, there is nothing in the book about Berkshire?s investment in BNSF, by far the largest investment of Buffett?s entire investing career, one that was so large it cost the company its triple-A rating. There is nothing in the book about what I think is one of the most interesting phases of Buffett?s investing career, that is, his opportunistic investment of $15.6 billion in the 25 days of panic that followed the Lehman bankruptcy. There is nothing in the book about the series of unprecedented moves Buffett has made in recent years, including, for example, Berkshire?s?$10 billion investment in IBM (following years of repeated statements that Buffett would never invest in technology because he doesn?t understand it) or Berkshire?s 2010 move to buyback its own shares.

?

And in an omission that is common among all of the various Buffett biographies, there is little in the book about the criminal prosecution of the top officers of what was at the time?the largest Berkshire subsidiary, General Re, owing to a complex, appearances-only transaction between Gen Re and AIG, of which Buffett may well have been aware at the time and with which Buffett may even have been involved.?We don?t know much about whether or not Buffett was involved or not, as to this date no one, especially not Buffett, has provided a comprehensive written account of the events from Buffett?s perspective. (More disclosure: During the relevant period, I worked at a subsidiary of Gen Re.)

?

In addition, one of the great strengths of the magazine?s coverage of Buffett ? that is, Loomis?s privileged access to Buffett -- may also be another of the book?s shortcomings. By her own admission, Loomis is not objective about Buffett. Her biases are well-disclosed ? she describes herself as Buffett?s ?close friend.? Over the years, Loomis controlled much of the magazine?s content about Buffett, either by writing it herself or by managing the editorial process of others? articles. The result is that some of the magazine?s Buffett coverage, especially when read in quick succession?as this book?s format requires, starts to feel like hagiography.

?

In short, while I think this new book is great and I have no trouble recommending it, in my view, the quintessential Buffett business biography still has yet to be written. I will say that for anyone interested in getting a handle on Buffett?s investing philosophy and business approach, as well as on the early days of his business career, the best bet may be Roger Lowenstein?s 1995 bio entitled Buffett: The Making of an American Capitalist. Indeed, the Bill Gates book review I mentioned above was written about Lowenstein?s book, of which Gates said ?until Warren writes his own book, this is the one to read.?

?

I have managed to get this far in my review of Loomis?s book about Buffett without mentioning what is by far its best part ? that is, the numerous pieces written by Buffett himself that are interspersed throughout the book. One of the most interesting items is an article Buffett wrote for the magazine in May 1977 entitled ?How Inflation Swindles the Equity Investor? (a version of which appears here). ?I had not previously read this article, but it may be the single best piece I have ever read encapsulating Buffett?s conception of equity investing. It also reflects a detailed and edifying analysis of the dangers economic inflation poses, a theme to which Buffett has returned time and again over the years (Including his provocative essay in his 2011 letter to Berkshire shareholders about investing in gold).

?

The fact that the best parts of this book are the ones that Buffett himself wrote suggests that the optimal approach to trying to understand Buffett may be to just cut to the chase and read Buffett?s own personal anthology, in the form of his annual letters to Berkshire shareholders. Thirty-five years? worth of the letters is freely available on Berkshire?s website, here. My own analysis of the most recent years? letters, along with my other writings about Buffett, can be found here.

?

Some readers may well find it a daunting task to try to work through hundreds of pages of the shareholder letters. Here?s a secret: there is a shortcut. George Washington Law School Professor Lawrence Cunningham has compiled an indexed, thematically arranged anthology of Buffett?s writings in a splendid book entitled The Essays of Warren Buffett: Lessons for Corporate America, the most recent edition of which can be found here. As I noted in my review of an earlier edition of Cunningham?s book, here, ?Cunningham has done a masterful job distilling Buffett?s writings and organizing them according to topic. This arrangement not only facilitates a quick reference to Buffett?s comments on any given topic, but it also provides insight into how Buffett?s views on the topic may have evolved over time.?

?

For readers who may be interested, my review of Alice Schroeder?s Buffett biography can be found here.

?

The Wit and Wisdom of the Sage of Omaha: One of the great pleasures of reading (or just reading about) Buffet?s various essays is his gift for the homey aphorism, often told with great humor. Loomis?s book captures a few of the good ones, including Buffett?s own summary of his experiences running (and saving) Salomon: ?I felt like the drama critic who wrote, ?I would have enjoyed the play except that I had an unfortunate seat. It faced the stage.??

?

Loomis also recounts some career advice Buffett gave to an audience of University of Washington business school students: ?I?d advise you when you go out to work , work for an organization of people you admire, because it will turn you on. I always worry about people who say, ?I?m going to do this for ten years. I really don?t like it very well. And then I?ll do this?? That?s a little like saving up sex for your old age. Not a very good idea.?

?

Some of my favorite Buffet anecdotes appear in his letters to Berkshire shareholders. In his 1986 letter, he wrote about the tailor who went to see the Pope, whose friends asked him what the Pope is like. Buffett writes that ?our hero wasted no words: ?He?s a forty-four medium.?? Another favorite is the story about the man who asked his vet what to do for his horse that limped sometimes but seemed fine at other times. Buffett states that ?the vet?s reply was pointed: ?No problem ? when he?s walking fine, sell him.??

?

My own personal favorite, from the 1985 letter, is one that I have quoted previously on this blog, but I like it so much, I am reproducing it again here:

?

An oil prospector, moving to his heavenly reward, was met by St. Peter with bad news. ?You?re qualified for residence?, said St. Peter, ?but, as you can see, the compound reserved for oil men is packed. There?s no way to squeeze you in.? After thinking a moment, the prospector asked if he might say just four words to the present occupants. That seemed harmless to St. Peter, so the prospector cupped his hands and yelled, ?Oil discovered in hell.? Immediately the gate to the compound opened and all of the oil men marched out to head for the nether regions. Impressed, St. Peter invited the prospector to move in and make himself comfortable. The prospector paused. ?No,? he said, ?I think I?ll go along with the rest of the boys. There might be some truth to that rumor after all.?

?

Source: http://www.dandodiary.com/2012/11/articles/warren-buffett/book-review-tap-dancing-to-work-the-latest-buffett-bio/

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Exploring post-divorce feelings may not help, study claims - Marilyn ...

Keeping a diary to explore your emotions after a divorce may do more harm than good, according to a new study from the University of Arizona.

Writing is a tool recommended by some therapists to encourage emotional healing after stressful life changes like divorce. The study, set to be published in a forthcoming issue of the journal Clinical Psychological Science, examined the effect of three different styles of diary writing amongst 90 divorced or separated people. One group was asked to write diaries freely exploring their feelings and emotions; a second was also asked to write about their emotions, but in a narrative structure; and a third, the control group, was asked to keep a journal about their every day activities but not include any reference to their emotions.

The original aim of the study was to explore the effectiveness of the two styles of emotional writing but after eight months, the researchers found that the non-emotional approach used by the control group was actually the most effective at promoting emotional healing, especially amongst a type of people referred to in the study as ?high ruminators?. These were defined as people who ?have a tendency to ruminate on their [failed relationship], brood on their experience and go over it and over it and over it again.?

Psychological scientist David Sbarra said dwelling on the past could be unhelpful. ?If a person goes over and over something in their head, and then you say, ?Write down your deepest darkest thoughts and go over it again,? we will intensify their distress.?

He added:

?If you?re someone who tends to be totally in your head and go over and over what happened and why it happened, you need to get out of your head and just start thinking about how you?re going to put your life back together and organize your time.?

Photo by?Barnaby Dorfman?under a Creative Commons licence?

?

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Source: http://www.marilynstowe.co.uk/2012/11/30/exploring-post-divorce-feelings-may-not-help-study-claims/

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Affordable, healthy homes increasingly out of reach for Kiwi families ...

Young families are being locked out of home ownership by rising house prices, and high rents

New statistics show that home ownership has fallen to a new low and families are increasingly being locked into unaffordable renting, Green Party housing spokesperson Holly Walker said today.

The Household Economic Survey, released by Statistics New Zealand today, shows that the homeownership rate, including homes owned by family trusts, has fallen from 70% five years ago to 65% in 2012. A record 562,000 families now pay rent, up 106,000 in five years.

The figures show families locked into renting are finding housing costs increasingly unaffordable with 215,000 renting families now paying over 30% of their incomes on housing up from 181,000 in 2008 when this figure was first reported. 30% of income is the generally recognised affordability limit for housing.

"Young families are being locked out of home ownership by rising house prices, and high rents," said Ms Walker.

"The homeownership rate has plunged to just 65% and a record 562,000 families are renting. More than 200,000 families are now paying over 30% of their income on rent.

"Young families are locked in a catch-22 situation. They can't afford to compete with wealthy property investors to buy their own homes, and they can't save up a decent deposit because those property investors demand high rents to make a profit. Instead, they are stuck paying a large slice of their incomes for homes that are often poorly insulated and unhealthy.

"Neither National's plan for 600 expensive houses in Hobsonville nor Labour's plan to get more affordable housing to market address the problem that most renting families are unable to get together a deposit in the first place. Nor will they address the fact that many rentals are poorly insulated.

"A Green Party Member's Bill, the Energy Efficiency and Conservation (Warm Healthy Rentals Warrant of Fitness) Amendment Bill, currently in the ballot would address part of the problem by setting insulation standards for rental properties, ensuring that the over half a million families who are renting have warm, healthy homes to live in.

"The Heat Smart scheme has proven government can successfully work alongside business and community groups to fix a housing problem while easing the cost for families in need. We need a similar solution on affordable housing," said Ms Walker.

Source: http://www.greens.org.nz/press-releases/affordable-healthy-homes-increasingly-out-reach-kiwi-families

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Russian mafia whistleblower, 44, found dead in UK

WEYBRIDGE, England/LONDON (Reuters) - A Russian businessman helping Swiss prosecutors uncover a powerful fraud syndicate has died in unexplained circumstances near his mansion in Britain, in a chilling twist to a Russian mafia scandal that has strained Moscow's ties with the West.

Alexander Perepilichny, 44, sought refuge in Britain three years ago and had been helping a Swiss investigation into a Russian money-laundering scheme by providing evidence against corrupt officials, his colleagues and media reports said.

He has also provided evidence against those linked to the 2009 death of anti-corruption lawyer Sergei Magnitsky, a case that caused an international outcry and prompted the United States to push for a bill cracking down on Russian corruption.

Perepilichny, a Russian citizen, collapsed and died not far from his home on an upmarket, heavily protected estate in the county of Surrey, south of London, on November 10.

He is now the fourth person linked to the Magnitsky case to have died in strange circumstances.

"It is being treated as unexplained," a police spokeswoman said. "A post-mortem examination was carried out which was inconclusive. So further tests are now being carried out."

Locals at the estate - dubbed as Britain's Beverly Hills and ringed by neatly trimmed golf courses and security check points - told Reuters that Perepilichny's body, clad in running gear, was found after dark at the top of a hill.

A shaky mobile phone video clip shot by Liam Walsh, a 24-year-old local chef, showed a motionless body of what he said was Perepilichny stretched out on the side of a deserted lane lit by the light of a lone lamp-post.

"He wasn't breathing. We had to get him on the back and start doing CPR (first aid). He was probably dead for a while," Walsh told Reuters as unmarked security cars patrolled the immaculately maintained estate.

Far beyond Russia's borders, Magnitsky's death has become a symbol of corruption in Russia and the abuse of those who challenge the authorities there.

This month the U.S. House of Representatives voted overwhelmingly to "name and shame" Russian rights violators as part of a broader trade bill, brushing off warnings from Moscow that the move would damage relations.

William Browder, a former employer of Magnitsky and a prominent London-based investor, said Perepilichny had come forward in 2010 with evidence involving the Magnitsky case that subsequently helped Swiss prosecutors open their investigation.

"Alexander Perepilichny approached us in 2010 as a whistleblower with evidence about the complicity of a number of Russian government officials in the theft of $230 million which Sergei Magnitsky had uncovered," said Browder, founder of Hermitage Capital Management.

"He provided us with copies of many of the original bank documents. In January 2011, Hermitage filed an application to the Swiss authorities seeking an investigation. It was announced in March that the Swiss prosecutor's office opened an investigation and froze the assets in a number of accounts."

Browder, whose grandfather was the general secretary of the American Communist Party, was one of the biggest Western investors in Russia but was barred from Russia in late 2005 and most of his staff left the country as Hermitage found itself coming under increasing official pressure.

Magnitsky was jailed in 2008 on suspicion of tax evasion and fraud, charges that colleagues say were fabricated by police investigators he had accused of stealing $230 million from the state through fraudulent tax refunds. The Kremlin's own human rights council has said Magnitsky was probably beaten to death.

News of Perepilichny's death initially appeared on Wednesday in a report in Britain's Independent newspaper, which is backed by Alexander Lebedev, a Russian billionaire who has spoken out publicly against the Kremlin.

British media said Perepilichny appeared to be in good health before he collapsed in the evening outside St George's Hill, one of Britain's most exclusive estates, where he was renting a house for 12,500 pounds ($20,000) a month.

St George's Hill is home to many big names in the financial and celebrity circles, its long list of one-time tenants including Elton John and Ringo Starr.

MAFIA STATE

Leaked secret diplomatic cables from the U.S. embassy in Moscow once described Russia as a "virtual mafia state", and London has long been the chosen destination for Russians seeking refuge from trouble at home.

But concerns have been growing in recent years that Britain might be turning into a playground for Russian mobsters as gangland violence seems to be spilling over Russian borders.

In April, a former Russian banker was shot near London's Canary Wharf financial district, sending a chill through the immigrant community. In 2006, former Russian spy Alexander Litvinenko died after drinking tea poisoned with polonium-210.

Asked about Perepilichny's case, Swiss prosecutors said it started its criminal investigation in March 2011 following a complaint made by London law firm Brown Rudnick filed on behalf of Hermitage Capital Management.

"Concerning the death of Mr Perepilichny and its consequences on the criminal proceedings, we'd like to stress that our strength resides in our ability to minimise the influence of such a regretful event on our investigation," the Swiss Office of the Attorney General said in a statement.

"A good cooperation with other judicial authorities is also essential to carry on our investigation efficiently."

Perepilichny was also a witness against Russia's notorious Klyuyev Group, a murky network of officials and underworld figures implicated in tax fraud who used European bank accounts to buy luxury property in Dubai and Montenegro, The Independent reported.

"Perepilichny was the guy who brought all the evidence they needed to open the investigation," a source told The Independent. "He brought with him records of shell companies, Credit Suisse accounts, property transactions. The whole lot."

(Additional reporting by Martin de Sa'Pinto in Switzerland; Writing by Maria Golovnina)

Source: http://news.yahoo.com/russian-mafia-whistleblower-found-dead-outside-uk-mansion-142346341--sector.html

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The reviews are in ? appeal immediately (Powerlineblog)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/267223122?client_source=feed&format=rss

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Workers' Comp For Food Trucks? | Southern States Insurance


There are thousands of workers? compensation claims every year. Is your mobile food truck business at an even greater risk for employee injury? Southern States Insurance agency can help you figure it all out.

If you own and run your business out of a food truck, the last thing you probably are thinking of is having workers? compensation. You know you need the general liability insurance to be able to use a private lot or attend an event, but why would you need workers? comp?

Food trucks today cater to a new market of foodies and gourmet snack lovers; gone are the days of generic food trucks that served construction workers. Now food trucks are something sought out, a destination instead of a convenience. As a food truck owner, you spend quality time and money branding your company, creating a menu, launching a website, Tweeting and using Facebook. You are passionate about your food and business and you want others to be too! So why would you risk all of that hard work per chance an employee was injured at work?

Who qualifies as an employee?

It?s important to understand who actual qualifies as an employee. An employee is someone who is working for another person, business or entity in return for some sort of payment. That means even if your friends or family members are helping you out, they too qualify as an employee, and therefore must be covered for workers? compensation. You may want to employ independent contractors, but in most circumstances there is no such thing as an independent contractor on a food truck.

What happens if I don?t have coverage?

Workers? compensation regulations and fines vary per state, so it is a good idea to do the research depending on where you operate. In the State of Georgia, if you regularly employ three or more persons at your business, you are required to provide the benefits. This includes full-time and regular part-time employees. If an employee is injured on the job, you will have to pay two-thirds of their wages and medical expenses till he/she can work again. Even if you have less than three employees at your business, if any of them is injured, you are required to cover their workers? compensation benefits. With workers? comp coverage, this burden will be lifted.

The importance of having workers? compensation for your food truck should be one of your top priorities. Accidents in the work place are unavoidable, but the risk always increased when your business is mobile. Southern States Insurance wants you to find the perfect coverage for your food truck business. We would love to give you a free quote and help your dreams thrive!

Related posts:

  1. Workers Compensation Insurance: A Guide To How It Works And Getting Cheap Quotes
  2. The Buzz About Workers Compensation Insurance And Your Hair Salon Coverage
  3. Having Difficulty Obtaining Worker?s Compensation Insurance For Your Staffing Firm?
  4. Cyber Liability ? Liability Insurance For The Internet
  5. Assisted Living Insurance Tips For Protecting Your Patients

Source: http://southernstatesinsurance.com/workers-comp-for-food-trucks/

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Thursday, November 29, 2012

Oil rises on higher economic growth expectation

NEW YORK (AP) ? The price of oil rose Thursday on an improved reading on U.S economic growth while lawmakers continued their tussle over the "fiscal cliff."

The Commerce Department Thursday raised its estimate for U.S. economic growth to an annual rate of 2.7 percent in the summer quarter of this year. That's much higher than the 2 percent rate estimated a month ago and more than twice the 1.3 percent rate in the three previous months.

Also Thursday The National Association of Realtors said its seasonally adjusted pending home sales index rose in October to its highest level in nearly six years.

Any sign the economic recovery is picking up can be a catalyst for energy prices.

Benchmark crude rose $1.58 to close at $88.07.

Falling prices at the gas pump could also drive Americans to spend more money on other things, like holiday gifts, further fueling the economy. The national average for a gallon of regular has been inching lower and is now $3.41. That is down about 12 cents from a month ago ? although still higher than a year ago.

There was no progress in closely watched budget talks in Washington. Lawmakers are trying to hammer out a deal to avoid a series of tax increases and spending cuts slated to start in January that economists warn would send the country back into recession.

House Speaker John Boehner accused Democrats of failing to outline specific cuts to benefit programs, which Republicans contend must be part of any deal. The White House and other Democrats said the Republicans were the ones holding things up.

In other trading, Brent crude, which is used to price international varieties of oil, rose $1.25 to $110.76 per barrel on the ICE Futures Exchange in London.

Other futures on the New York Mercantile Exchange:

? Heating oil rose 3.3 cents to $3.04 a gallon

? Natural gas fell 15.3 cents to $3.65 per 1,000 cubic feet

? Wholesale gasoline gained 5.3 cents to $2.79 a gallon

Source: http://news.yahoo.com/oil-rises-higher-economic-growth-expectation-204252106--finance.html

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Samsung Galaxy S III mini review: a small Galaxy with few stars

Samsung Galaxy S III mini review: a small Galaxy with few stars

Samsung made a bold move when it announced the Galaxy S III mini. Here was an Android phone with the potential to take the iPhone 5 head-on. While the original Galaxy S III is clearly the flagship, its 4.8-inch display means it's literally too much for some people to handle. By matching Apple's screen size inch for inch, it could have been pitched as a device aimed at winning over some iOS fence-sitters. However, when you look at the specifications: a dual-core 1GHz processor, WVGA (800 x 480) display and a 5-megapixel camera, it's clear that Samsung had other ideas, opting to fish for a more mid-range customer instead.

Fast forward to the present, and it's no longer a matter of intellectual debate as to what the mini is all about: the phone is here, and on sale in much of Europe for £299 / €379. So hubris, brand appeal and pundit talk aside, is this the real-deal Galaxy S III, just for smaller hands? Or is it a budget phone simply wearing its elder sibling's tuxedo to the ball? We spent some time getting to know the phone in an attempt to find out.

Continue reading Samsung Galaxy S III mini review: a small Galaxy with few stars

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Source: http://www.engadget.com/2012/11/29/samsung-galaxy-s-iii-mini-review/

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The high-risk history of Scaffold Matches

All WWE programming, talent names, images, likenesses, slogans, wrestling moves, trademarks, logos and copyrights are the exclusive property of WWE, Inc. and its subsidiaries. All other trademarks, logos and copyrights are the property of their respective owners. ? 2012 WWE, Inc. All Rights Reserved. This website is based in the United States. By submitting personal information to this website you consent to your information being maintained in the U.S., subject to applicable U.S. laws. U.S. law may be different than the law of your home country. WrestleMania XXIX (NY/NJ) logo TM & ? 2012 WWE. All Rights Reserved. The Empire State Building design is a registered trademark and used with permission by ESBC.

Source: http://www.wwe.com/classics/classic-lists/history-scaffold-matches

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African Union asks UN for immediate action on Mali

DAKAR, Senegal (AP) ? In an open letter Thursday to U.N. Secretary-General Ban Ki-moon, the president of the African Union urged the U.N. to take immediate military action in northern Mali, which was seized by al-Qaida-linked rebels earlier this year.

Yayi Boni, the president of Benin who is also head of the African Union, said any reticence on the part of the U.N. will be interpreted as a sign of weakness by the terrorists now operating in Mali. The AU is waiting for the U.N. to sign off on a military plan to take back the occupied territory, and the Security Council is expected to discuss it in coming days.

In a report to the Security Council late Wednesday, Ban said the AU plan "needs to be developed further" because fundamental questions on how the force will be led, trained and equipped. Ban acknowledged that with each day, al-Qaida-linked fighters were becoming further entrenched in northern Mali, but he cautioned that a botched military operation could result in human rights abuses.

The sprawling African nation of Mali, once an example of a stable democracy, fell apart in March following a coup by junior officers. In the uncertainty that ensued, rebels including at least three groups with ties to al-Qaida grabbed control of the nation's distant north. The Islamists now control an area the size of France or Texas, an enormous triangle of land that includes borders with Mauritania, Algeria and Niger.

Two weeks ago, the African Union asked the U.N. to endorse a military intervention to free northern Mali, calling for 3,300 African soldiers to be deployed for one year. A U.S.-based counterterrorism official who saw the military plan said it was "amateurish" and had "huge, gaping holes." The official insisted on anonymity because he was not authorized to speak on the matter.

Boni, in his letter, said Africa was counting on the U.N. to take decisive action. "I need to tell you with how much impatience the African continent is awaiting a strong message from the international community regarding the resolution of the crisis in Mali ... What we need to avoid is the impression that we are lacking in resolve in the face of these determined terrorists," he said.

The most feared group in northern Mali is al-Qaida in the Islamic Maghreb, or AQIM, al-Qaida's North African branch, which is holding at least seven French hostages, including a 61-year-old man kidnapped last week.

On Thursday, an AQIM leader, Abu Musab Abdul Wadud, released a video urging Malians to reject any foreign intervention in their country. He warned French President Francois Hollande that he was "digging the graves" of the French hostages by pushing for an intervention, according to a transcript published by Washington-based SITE Intelligence.

Also Thursday, Islamists meted out the latest Shariah punishment in northern city of Timbuktu. Six young men and women were each given 100 lashes for having talked to each other on city streets, witnesses said.

___

Associated Press writer Virgile Ahissou contributed to this report from Cotonou, Benin.

Source: http://news.yahoo.com/african-union-asks-un-immediate-action-mali-172902123.html

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Press release distribution company PR NewsChannel launches ...

Sorry, Readability was unable to parse this page for content.

Source: http://www.prnewschannel.com/2012/11/29/press-release-distribution-company-pr-newschannel-launches-preferred-vip-savings-program/

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Former Skins Coach/player Jack Pardee terminally ill with cancer


Real sad news. His 'run and shoot' Oilers in their powder blue with Moon, Givens, Jeferries and co are still one of my favourite non-'Skins teams.

Here's praying you have as comfortable as possible final time on this Earth Coach.

Thanks for the memories, and your efforts here.

Hail.

Source: http://www.extremeskins.com/showthread.php?374504-Former-Skins-Coach-player-Jack-Pardee-terminally-ill-with-cancer&goto=newpost

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House prices steady in November - Nationwide

NEW YORK (Reuters) - A young model was either insane, or a calculating, quick-thinking murderer who feigned mental illness when he killed and castrated his lover, a prominent Portuguese journalist, in their New York hotel room last year, a jury heard on Wednesday. No one disputes that Renato Seabra, 22, killed Carlos Castro, 65, in January 2011. Seabra pleaded not guilty by reason of insanity to a charge of second degree murder, and his trial reached closing arguments at Manhattan criminal court. ...

Source: http://news.yahoo.com/house-prices-steady-november-nationwide-070345078--business.html

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Susan Rice fails in attempt to win over Republican senators on Benghazi response

WASHINGTON - Susan Rice's closed-door meeting on Tuesday with three Republican lawmakers did nothing to ease their criticisms of the UN ambassador's public proclamations over the September attack on the U.S. consulate in Libya that killed four Americans, including envoy Chris Stevens.

"I'm more disturbed now than I was before," South Carolina Sen. Lindsey Graham told reporters after Rice explained why she initially characterized the Benghazi attack as a spontaneous eruption of violence over an anti-Islam video.

"I think it does not do justice to the reality at the time and in hindsight clearly was completely wrong.... In real time, it was a statement disconnected from reality."

Rice's 90-minute meeting with Graham and fellow senators John McCain and Kelly Ayotte came amid the roar of speculation in the U.S. capital that she's about to be tapped by the Obama administration, possibly as early as this week, to replace Hillary Clinton as secretary of state.

Clinton wants out of the job so Rice, who's been serving as the U.S. ambassador to the United Nations since 2009, is making the rounds on Capitol Hill this week on an apparent "charm offensive" aimed at getting lawmakers behind her potential nomination.

Her first foray onto the Hill on Tuesday with acting CIA director Michael Morell, however, backfired badly, thanks to the trio of senators who have been bitterly maligning her Benghazi response for weeks.

All three of them emerged from the meeting to say they're more bothered now about her public remarks on Sunday morning talk shows a few days after the Sept. 11 attack than they were before she attempted to explain herself.

"I'm significantly troubled by the answers we got and didn't get," McCain said.

"It was clear that the information she gave the American people was incorrect when she said that it was a spontaneous demonstration triggered by a hateful group."

Ayotte, meantime, said she had "many more questions that need to be answered" and suggested she'd vote against Rice's nomination as secretary of state.

Rice, 48, has said her public remarks about the Benghazi attack were based on talking points provided by U.S. intelligence agencies.

Those in intelligence circles suggest the talking points were deliberately vague in order to protect covert operations in Libya in the aftermath of the attack, adding that an investigation was still underway when Rice made the rounds of talk shows on Sept. 16.

Republicans, meantime, suspect Rice was covering up for U.S. President Barack Obama, charging the administration didn't want an al-Qaida terrorist attack to taint his re-election chances.

Obama has defended Rice, most fiercely in a White House news conference held soon after his re-election.

White House spokesman Jay Carney came to Rice's defence again on Tuesday, shortly after her ill-fated visit to Capitol Hill.

"Ambassador Rice has no responsibility for collecting, analyzing and providing intelligence, nor does she have responsibility ... for diplomatic security around the globe," he said.

"The focus on ? some might say obsession (with) ? comments made on Sunday shows seems to me, and to many, to be misplaced. What is the point of the focus on this?"

Rice, a Rhodes scholar who's married to Canadian television producer Ian Cameron, has risen through Democratic ranks over the years to counsel presidential candidates that include Michael Dukakis and John Kerry, himself a potential Hillary Clinton replacement.

She has an impressive pedigree ? her father was the first black governor of the Federal Reserve Board, her mother a renowned education scholar ? but Rice's legendary abrasiveness has prompted misgivings about her suitability for the job from both the left and right.

"She is ill-equipped to be the nation's top diplomat for reasons that have little to do with Libya," Dana Milbank, a left-leaning Washington Post columnist, wrote recently in a piece that recounted how she once gave respected diplomat Richard Holbrooke the middle finger when she worked in the Bill Clinton White House.

He called her an "undiplomatic diplomat."

The New York Times' Maureen Dowd, also a liberal columnist, took aim as well, arguing Rice's foreign policy stances are primarily motivated by professional ambitions.

Rice also has a reportedly uneasy relationship with Hillary Clinton. She was among the first of Bill Clinton's former officials to back Obama over his wife in 2008, and frequently criticized her throughout primary season.

In 2008, she also repeatedly slagged McCain, whose memory is long. Among other insults, she mocked his trip to Iraq during the presidential election campaign and called him reckless and belligerent.

Some in the international community are reportedly nervous about the prospect of Rice as secretary of state. An anonymous Russian foreign ministry official was recently quoted describing her as "too ambitious and aggressive," adding her appointment would strain relations between Russia and the United States.

Under Bill Clinton, Rice had a critical say in several foreign policy decisions ? some of them controversial. Among other moves, she advised against accepting Sudan's help in capturing Osama bin Laden in the 1990s.

She later expressed regret over the Clinton administration's failure to prevent massive genocide in Rwanda in 1994. Canada's Romeo Dallaire, head of the overwhelmed UN peacekeeping forces at the time, had urged the international community to take action.

"I swore to myself that if I ever faced such a crisis again, I would come down on the side of dramatic action, going down in flames if that was required," Rice later recounted.

There's even a Canadian angle to some of her public remarks. As Obama ran for president, Rice insisted his campaign had never assured Canadian officials that his opposition to the North American Free Trade Agreement was "just politics."

"The Canadian ambassador issued a statement that that story was absolutely false," Rice said in a television interview, making reference to Michael Wilson's denial of a report that an Obama official had personally made NAFTA assurances to him in a phone call.

"There had been no contact. There had been no discussions on NAFTA."

Obama later acknowledged Austan Goolsbee, his economic adviser, had in fact talked to a senior Canadian official in Chicago about his stance on the trade pact.

Rice certainly has no shortage of defenders ? including her ninth grade teacher, who wrote the Post to dispute Milbank's column.

"She was one of the most outstanding students I encountered in my 40-year teaching career," wrote John Wood of D.C.'s National Cathedral School.

A sole Republican is also defending her. Jon Huntsman, the former Republican presidential hopeful, said that criticism of Rice's failure to immediately describe the Benghazi attack as an act of terrorism was unfair.

"The issue of Benghazi, I think you can attribute to the fog of war, more than anything else," Huntsman, the former governor of Utah, said this week.

"It takes a while to sort through the details. And it doesn't do a whole lot of good for the political class to point fingers before you even know what was behind it."

Source: http://news.yahoo.com/susan-rice-fails-attempt-win-over-republican-senators-203804229.html

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When your boss doesn't have a clue ? Business Management Daily ...

An incompetent boss?one who is functionally inadequate or insufficient in knowledge, skills, judgment or strength?is annoying at best and damaging to your career at worst.

To keep your career moving forward in spite of a clueless boss, Dorothy Tannahill-Moran recommends that you:

  • Manage yourself. You don?t need a title to be a leader. If you know your stuff, you can chart your own path toward objectives that will have a positive effect on your department and the company. Just remember to keep your boss in the loop.
  • Identify the pain points. Figure out the main negative effects of your boss?s incompetence and come up with a plan to overcome them.
  • Become a teacher. Sometimes you have to train a boss to get him up to speed, so share your knowledge.
  • Find a mentor. Pick someone more competent in your company and ask him to be your mentor.
  • Get a new job. When you think you?ve tried everything, it may be time to find a new job and move on.

? Adapted from ?5 Ways to Deal With an Incompetent Boss,? Dorothy Tannahill-Moran, Careerealism.

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